Delayed Cancer Diagnosis: Bibliometric Analysisand Its Relevance for Health Systems

Delayed Cancer Diagnosis: Bibliometric Analysisand Its Relevance for Health Systems

Authors

  • María del Mar Vargas Diaz Universidad del Valle
  • María Fernanda Tobar Blandón Escuela de salud pública
  • Óscar Marino López Mallama Universidad del Valle https://orcid.org/0000-0002-3543-9123
  • Alexander Almeida Espinosa Universidad del Valle
  • Carlos Andrés Fandiño-Losada Universidad del Valle

DOI:

https://doi.org/10.30854/rss65n15

Keywords:

cancer, delayed diagnosis, neoplasm staging, health care systems, health policy , (obtained from DeCS/MeSH)

Abstract

Objective: To analyze scientific production and trends regarding the relationship between cancer, delayed diagnosis, and health systems from a comprehensive perspective. Methodology: Bibliometric techniques were applied using the Scopus database, including productivity indicators and bibliographic coupling network analysis. Temporal trends and distribution by authors, journals, countries, and areas of knowledge were examined. Results: Delayed diagnosis is explained by personal factors (age, education, and beliefs), social factors (economic, cultural, and geographic conditions), and structural factors (institutional fragmentation and weak coordination among actors). Five research  clusters were identified: determinants of delayed diagnosis, therapeutic options, socioeconomic factors, the impact of COVID-19, and life expectancy as a conditioning factor in treatment decisions. Conclusions: Reducing delayed diagnoses requires strategies at the macro, meso, and micro levels, prioritizing health promotion, disease prevention, and the guarantee of the right to life and health. 

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Author Biographies

  • María del Mar Vargas Diaz, Universidad del Valle

    Universidad del Valle

  • María Fernanda Tobar Blandón, Escuela de salud pública

    Escuela de salud pública

  • Óscar Marino López Mallama, Universidad del Valle

    Professor Universidad del Valle. Institución Universitaria Antonio Camacho

  • Alexander Almeida Espinosa, Universidad del Valle

    Docente de la Universidad del Valle

  • Carlos Andrés Fandiño-Losada, Universidad del Valle

    Universidad del Valle

References

Acuña, L., & Ramírez, P. (2018). Cancer Risk Management in Colombia, 2016. Colombia Médica, 49(1), 128-134. https://doi.org/10.25100/cm.v49i1.3882

Aiello, E., Boudreau, D., Chubak J., Yu, O, Fujii, M., Chestnut, J., & Buist, D. (2012). Patient-Reported Discontinuation of Endocrine Therapy and Related Adverse Effects Among Women With Early-Stage Breast Cancer. Journal of Oncology Practice, 8(6), 149-157. https://doi.org/10.1200/JOP.2012.000543

Altekruse, S., McGlynn, K., & Reichman, M. (2009). Hepatocellular Carcinoma Incidence, Mortality, and Survival Trends in the United States from 1975 to 2005. Journal of Clinical Oncology, 27(9), 1485-1491. https://ascopubs.org/doi/10.1200/JCO.2008.20.7753

American Cancer Society. (2024a). Estadificación del cáncer. https://www.cancer.org/es/cancer/diagnostico-y-etapa-del-cancer/estadificacion-del-cancer.html

American Cancer Society. (2024b). Etapas del linfoma de Hodgkin. https://www.cancer.org/es/cancer/tipos/linfoma-hodgkin/deteccion-diagnostico-clasificacion-por-etapas/clasificacion-por-etapas.html

Bergin, R., Emery, J., Bollard, R., Falborg, A., Jensen, H., Weller, D., White, V et al. (2018). Rural–Urban Disparities in Time to Diagnosis and Treatment for Colorectal and Breast Cancer. Cancer Epidemiology, Biomarkers & Prevention, 27(9), 1036-1046. https://aacrjournals.org/cebp/article/27/9/1036/71690/Rural-Urban-Disparities-in-Time-to-Diagnosis-and

Bilimoria, K., Balch, C., Wayne, J., Chang, D., Palis, B., Dy, S., & Lange, J. (2009). Health Care System and Socioeconomic Factors Associated With Variance in Use of Sentinel Lymph Node Biopsy for Melanoma in the United States. Journal of Clinical Oncology, 27(11), 1857-1863. https://ascopubs.org/doi/10.1200/JCO.2008.18.7567

Bran, L., Valencia, A., Palacios, L., Gómez, S., Acevedo, Y. y Arias, C. (2020). Barreras de acceso del sistema de salud colombiano en zonas rurales: percepciones de usuarios del régimen subsidiado. Hacia la Promoción de la Salud, 25(2), 29-38. https://doi.org/10.17151/hpsal.2020.25.2.6

Brown, S., Castelli, M., Hunter, D., Erskine, J., Vedsted, P., Foot, C., & Rubin, G. (2014). How Might Healthcare Systems Influence Speed of Cancer Diagnosis: A Narrative Review. Social Science & Medicine, 116, 56-63. https://linkinghub.elsevier.com/retrieve/pii/S0277953614003980

Casella, D., Fusario, D., & Neri, A. (2021). New Safer Management for Breast Cancer Patients Who Need Neoadjuvant Therapy During SARS-COVID Pandemic. Breast Disease, 41(1), 1-3. https://doi.org/10.3233/BD-210007

Chen, A., Cronin, A., Weeks, J., Chrischilles, E., Malin, J., Hayman, J., & Schrag, D. (2013). Expectations About the Effectiveness of Radiation Therapy Among Patients With Incurable Lung Cancer. Journal of Clinical Oncology, 31(21), 2730-2735. https://ascopubs.org/doi/10.1200/JCO.2012.48.5748

Cuenta de Alto Costo [CAC]. (2015). Situación del cáncer en la población adulta atendida en el SGSSS de Colombia 2015. https://cuentadealtocosto.org/site/publicaciones/situacion-del-cancer-en-la-poblacion-adulta-atendida-en-elsgsss-de-colombia/

Desch, C., McNiff, K., Schneider, E., Schrag, D., McClure, J., Lepisto, E., & Edge, S. (2008). American Society of Clinical Oncology/National Comprehensive Cancer Network Quality Measures. Journal of Clinical Oncology, 26(21), 3631-3637. https://ascopubs.org/doi/10.1200/JCO.2008.16.5068

Do Nascimento, J., da Silva, C., Gusmão-Cunha, A., Neto, M., & de Andrade, A. (2023). Effects of the COVID-19 Pandemic on Delays in Diagnosisto-Treatment Initiation for Breast Cancer in Brazil: a Nationwide Study. Ecancermedicalscience, 17, 1-18. https://doi.org/10.3332/ecancer.2023.1570

Donthu, N., Kumar, S., Mukherjee, D., Pandey, N., & Lim, W. (2021). How to Conduct a Bibliometric Analysis: An Overview and Guidelines. Journal of Business Research, 133, 285-296. https://linkinghub.elsevier.com/retrieve/pii/S0148296321003155

Eaglehouse, Y., Georg, M., Shriver, C., & Zhu, K. (2019). Time-to-Surgery and Overall Survival After Breast Cancer Diagnosis in a Universal Health System. Breast Cancer Research and Treatment, 178(2), 441-450. https://doi.org/10.1007/s10549-019-05404-8

Elkin, P., Mullin, S., Tetewsky, S., Resendez, S., McCray, W., Barbi, J., & Yendamuri, S. (2022). Identification of Patient Characteristics Associated With Survival Benefit from Metformin Treatment in Patients With Stage I Non–Small Cell Lung Cancer. The Journal of Thoracic and Cardiovascular Surgery, 164(5), 1318-1326. https://linkinghub.elsevier.com/retrieve/pii/S0022522322002410

Enewold, L., Zhu, K., Ron, E., Marrogi, A., Stojadinovic, A., Peoples, G., & Devesa, S. (2009). Rising Thyroid Cancer Incidence in the United States by Demographic and Tumor Characteristics, 1980-2005. Cancer Epidemiology Biomarkers & Prevention, 18(3), 784-791. https://aacrjournals.org/cebp/article/18/3/784/164680/Rising-Thyroid-Cancer-Incidence-in-the-United

Ferreira, A., Cintra, J., Fayer, V., Nogueira, M., Júnior, C., Bustamante-Teixeira, M. T., & Guerra, M. (2023). Breast Cancer Survival and the Health System in Brazil: An Analysis of Public and Private Healthcare. Frontiers in Oncology,13, 1-13. https://www.frontiersin.org/articles/10.3389/fonc.2023.927748/full

Hershman, D., Kushi, L., Shao, T., Buono, D., Kershenbaum, A., Tsai, W et al. (2010). Early Discontinuation and Nonadherence to Adjuvant Hormonal Therapy in a Cohort of 8,769 Early-Stage Breast Cancer Patients. Journal of Clinical Oncology, 28(27), 4120-4128. https://ascopubs.org/doi/10.1200/JCO.2009.25.9655

Instituto Nacional del Cáncer [NCI]. Definición de cáncer en estadio tardío. Diccionario de cáncer del NCI. https://www.cancer.gov/espanol/publicaciones/diccionarios/diccionario-cancer/def/cancer-en-estadio-tardio

Janik, A., Ryszko, A., & Szafraniec, M. (2020). Scientific Landscape of Smart and Sustainable Cities Literature: A Bibliometric Analysis. Sustainability, 12(3), 1-39. https://doi.org/10.3390/su12030779

Jiménez‐Pérez, M., & Thomas, D. (1999). Has the Use of Pap Smears Reduced the Risk of Invasive Cervical Cancer in Guadalajara, Mexico? International Journal of Cancer, 82(6), 804-809. https://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-0215(19990909)82:6<804::AID-IJC6>3.0.CO;2-N

Kohler, R., Gopal, S., Miller, A., Lee, C., Reeve, B., Weiner, B., & Wheeler, S. (2017). A Framework for Improving Early Detection of Breast Cancer in Sub-Saharan Africa: A Qualitative Study of Help-Seeking Behaviors Among Malawian Women. Patient Education and Counseling, 100(1), 167-173. https://linkinghub.elsevier.com/retrieve/pii/S0738399116303548

Lin, J., Gill, A., Zahm, S., Carter, C., Shriver, C., Nations, J et al. (2017). Metformin Use and Survival After Non‐Small Cell Lung Cancer: A Cohort Study in the US Military Health System. International Journal of Cancer, 141(2), 254-263. https://onlinelibrary.wiley.com/doi/10.1002/ijc.30724

Mack, J., Walling, A., Dy, S., Antonio, A, Adams, J., Keating, N., & Tisnado, D. (2015). Patient Beliefs that Chemotherapy May Be Curative and Care Received at the end of Life Among Patients With Metastatic Lung and Colorectal Cancer. Cancer, 121(11), 1891-1897. https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.29250

Martínez-Pérez, D., Gómez-Wolff, L., Ossa-Gómez, C., Hernández-Herrera, G., Rivas-Bedoya, Y., & García-García, H. (2020). Asociación entre retraso en el diagnóstico y estadio clínico avanzado de cáncer de mama al momento de la consulta en cuatro centros oncológicos de Medellín, Colombia,2017. Estudio de corte transversal. Revista Colombiana de Obstetricia y Ginecología, 71(2), 87-102. https://doi.org/10.18597/rcog.3410

McKenzie, F., Zietsman, A., Galukande, M., Anele, A., Adisa, C., Parham, G., & McCormack, V. (2018). Drivers of Advanced Stage at Breast Cancer Diagnosis in the Multicountry African Breast Cancer–Disparities in Outcomes (ABC‐DO) Study. International Journal of Cancer, 142(8), 1568-1579. https://onlinelibrary.wiley.com/doi/10.1002/ijc.31187

McMahon, D., Chemtai, L., Grant, M., Singh, R., Semeere, A., Byakwaga, H., Freeman, E et al. (2022). Understanding Diagnostic Delays for Kaposi Sarcoma in Kenya: A Qualitative Study. JAIDS Journal of Acquired Immune Deficiency Syndromes, 90(5), 494-503. https://journals.lww.com/10.1097/QAI.0000000000003011

Moreno, D. y Urrego, Z. (2022). Efectos de los artefactos explosivos sobre la salud auditiva de personas expuestas en conflictos armados. Hacia la Promoción de la Salud, 27(1), 191-212. https://revistasojs.ucaldas.edu.co/index.php/hacialapromociondelasalud/article/view/6761

Nila, S., Dutta, E., Prakash, S., Korula, S., & Oommen, A. (2024). Patient and Caregiver Perspectives of Select Non-Communicable Diseases in India: A Scoping Review. Plos One, 19(1), 1-20. https://dx.plos.org/10.1371/journal.pone.0296643

Organización Panamericana de la Salud [OPS]. (2024). Cáncer. OPS/OMS. https://www.paho.org/es/temas/cancer

Osorio-Andrade, C., Arango, C., & Rodríguez, A. (2023). Evolución de la investigación científica sobre Electronic Word of Mouth en la industria del turismo: un análisis bibliométrico. Estudios gerenciales, 39(166), 110-123. https://www.icesi.edu.co/revistas/index.php/estudios_gerenciales/article/view/5415

Price, A., Ndom, P., Atenguena, E., Mambou, J., & Ryder, R. (2012). Cancer Care Challenges in Developing Countries. Cancer, 118(14), 3627-3635. https://doi.org/10.1002/cncr.26681

Samadder, N., Curtin, K., Tuohy, T., Pappas, L., Boucher, K., Provenzale, D et al. (2014). Characteristics of Missed or Interval Colorectal Cancer and Patient Survival: A Population-Based Study. Gastroenterology, 146(4), 950-960. https://linkinghub.elsevier.com/retrieve/pii/S0016508514000262

Schmitt, M., Harbeck, N., Brünner, N., Jänicke, F., Meisner, C., Mühlenweg, B et al. (2011). Cancer Therapy Trials Employing Level-Of-Evidence-1 Disease Forecast Cancer Biomarkers uPA and its Inhibitor PAI-1. Expert Review of Molecular Diagnostics, 11(6), 617-634. https://doi.org/10.1586/erm.11.47

Shakarishvili, G., Lansang, M., Mitta, V., Bornemisza, O., Blakley, M., Kley, N., Burgess, C., & Atun, R. (2011). Health Systems Strengthening: A Common Classification and Framework for Investment Analysis. Health Policy and Planning, 26(4), 316-326. https://doi.org/10.1093/heapol/czq053

Shukla, A., Muhuri, P., & Abraham, A. (2020). A Bibliometric Analysis and Cutting-Edge Overview on Fuzzy Techniques in Big Data. Engineering Applications of Artificial Intelligence, 92, 1-18. https://linkinghub.elsevier.com/retrieve/pii/S0952197620300877

Soulos, P., Yu, J., Roberts, K., Raldow, A., Herrin, J., Long, J., & Gross, C. (2012). Assessing the Impact of a Cooperative Group Trial on Breast Cancer Care in the Medicare Population. Journal of Clinical Oncology, 30(14), 1601-1607. https://ascopubs.org/doi/10.1200/JCO.2011.39.4890

The Cancer Genome Atlas Network. (2012). Comprehensive Molecular Portraits of Human Breast Tumours. Nature. https://www.nature.com/articles/nature11412

Unger-Saldaña, K., Miranda, A., Zarco-Espinosa, G., Mainero-Ratchelous, F., Bargalló-Rocha, E., & Lázaro-León, J. (2015). Health System Delay and its Effect on Clinical Stage of Breast Cancer: Multicenter Study. Cancer, 121(13), 2198-2206. https://doi.org/10.1002/cncr.29331

Unión Internacional contra el Cáncer [UICC]. (2024). ¿Qué es el cáncer? World Cancer Day. https://www.worldcancerday.org/es/que-es-el-cancer

Walter, F., Mills, K., Mendonça, S., Abel, G., Basu, B., Carroll, N., Emery, J et al. (2016). Symptoms and Patient Factors Associated With Diagnostic Intervals for Pancreatic Cancer (SYMPTOM Pancreatic Study): A Prospective Cohort Study. The Lancet Gastroenterology & Hepatology, 1(4), 298-306. https://linkinghub.elsevier.com/retrieve/pii/S2468125316300796

Waltman, L., & van Eck, N. (2015). Field-Normalized Citation Impact Indicators and the Choice of an Appropriate Counting Method. Journal of Informetrics, 9(4), 872-894. https://linkinghub.elsevier.com/retrieve/pii/S1751157715300456

Ward, Z., Walbaum, M., Walbaum, B., Guzman, M., De la Jara, J, Nervi, B., & Atun, R. (2021). Estimating the Impact of the COVID-19 Pandemic on Diagnosis and Survival of Five Cancers in Chile from 2020 to 2030: A

Simulation-Based Analysis. The Lancet Oncology, 22(10), 1427-1437. https://linkinghub.elsevier.com/retrieve/pii/S1470204521004265

Zadnik, V., Mihor, A., Tomsic, S., Zagar, T., Bric, N., Lokar, K. & Oblak, I. (2020). Impact of COVID-19 on Cancer Diagnosis and Management in Slovenia–Preliminary Results. Radiology and Oncology, 54(3), 329-334. https://doi.org/10.2478/raon-2020-0048

Published

2026-01-01

How to Cite

Delayed Cancer Diagnosis: Bibliometric Analysisand Its Relevance for Health Systems: Delayed Cancer Diagnosis: Bibliometric Analysisand Its Relevance for Health Systems. (2026). ÁNFORA, 33(60), 218-247. https://doi.org/10.30854/rss65n15
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