Polyconsumption of Legal and Illegal Substances in TheElderly:
Comparison Between Medellin and Pereira
DOI:
https://doi.org/10.30854/anf.v32.n59.2025.1197Keywords:
Polypharmacy, Substance-related disorders, anging, Health, Social supportAbstract
Objective: To compare the poly-consumption of legal and illegal substances among elderly residents in the cities of Medellin and Pereira (Colombia). Methodology: Quantitative, cross-sectional study, with analytical scope, which explored the demographic, social and health characteristics associated with poly-drug use, defined as the concurrent use of two or more legal and/or illegal substances. A total of 1005
adults, randomly selected from their neighborhoods and homes, were surveyed through probability sampling in each city. Descriptive statistics and binomial regression
analysis were used in the analysis, with measures of association, hypothesis testing
and 95% confidence intervals. Results: The use of polypharmaceuticals was recorded in 66% of the elderly, with a higher frequency in Pereira (p<0.05). The associated demographic factors were: older than 70 years; in social: high self-esteem and perceived discrimination and health-related: experiencing pain, illness and poor sleep quality. The final model accounted for 20% of the variability observed in the use of polydrugs. Conclusions: No differences were found by city, but age, illness, and pain appear to be closely related to higher substance use; therefore, social engagement strategies and activities that promote distraction, energy expenditure, inclusion, and self-esteem are needed.
Downloads
References
Afonso, P., Afonso, M., Barbosa, G., & Justo, A. (2022). Hospitalization Due to Mental and Behavioral Disorders Caused by Use of Alcohol and Psychoactive Substances Among Older Adults and Elderly People in Brazil: A Cross-Sectional Study. Revista Paulista de Medicina, 140(2), 229-236. https://doi.org/10.1590/1516-3180.2021.0115.R1.22062021
Barreto, P., Pérez, M., Roa, M., López, A. y Rubiano, G. (2014). Consumo de sustancias psicoactivas legales e ilegales, factores de protección y de riesgo: estado actual. Revista Investigación en Salud Universidad de Boyacá, 2(1), 31-50.
https://revistasdigitales.uniboyaca.edu.co/index.php/rs/article/view/128
Bartleson, J., Radenkovic, D., Covarrubias, A., Furman, D., Winer, D., & Verdin, E. (2021). SARS-CoV-2, COVID-19 and the Ageing Immune System. Nature aging, 1(9), 769-782. https://doi.org/10.1038/s43587-021-00114-7
Cardona, D., Garzón, M., Muñoz, D. y Segura, A. (2021). Desafíos de la salud pública: transición demográfica, epidemiológica y sanitaria. En: Blanco, J. y Maya, J. (Eds), Salud Pública. Tomo I. 4ª (pp. 81-99). Corporación para Investigaciones Biológicas CIB.
Casas-Vásquez, P., Ortiz-Saavedra, P., Penny-Montenegro, E. (2016). Estrategias para optimizar el manejo farmacológico en el adulto mayor. Revista Peruana de Medicina Experimental y Salud Pública, 33(2), 335-341. https://dx.doi.org/10.17843/rpmesp.2016.332.2153
Castro-Rodríguez, J., Orozco-Hernández, J. y Marín-Medina, D. (2015). Polifarmacia y prescripción de medicamentos potencialmente no apropiados en ancianos. Revista Médica de Risaralda, 21(2), 52-57. https://dialnet.unirioja.es/servlet/articulo?codigo=5379847
Center for Substance Abuse Prevention, Substance Abuse and Mental Health Services Administration [SAMHSA] (2019). Medication, Alcohol, and Mental Health. SMA.
Centers for Disease Control and Prevention [CDC]. (2023). Factors That Affect Your Risk of Getting Very Sick from COVID-19. https://www.cdc.gov/coronavirus/2019-ncov/your-health/risks-getting-very-sick.html
Collins, R., Ellickson, P., & Bell, R. (1998). Simultaneous Polydrug Use Among Teens: Prevalence and Predictors. Journal of Substance Abuse, 10(3), 233-253. https://doi.org/10.1016/s0899-3289(99)00007-3
Colliver, J., Compton, W., Gfroerer, J., & Condon, T. (2006). Projecting Drug Use Among Aging Baby Boomers in 2020. Annals of Epidemiology, 16(4), 257-265. https://doi.org/10.1016/j.annepidem.2005.08.003
Connor, J., Gullo, M., White, A., & Kelly, A. (2014). Polysubstance Use: Diagnostic Challenges, Patterns of Use and Health. Current Opinion in Psychiatry, 27(4), 269-275. https://doi.org/10.1097/YCO.0000000000000069
De Joncheere, C. y Del Campo, R. (2021). Consumo de drogas entre personas mayores: una epidemia oculta. Diario El Universal. https://www.eluniversal.com.mx/opinion/cornelis-p-de-joncheere-y-raul-martin-del-campo-sanchez/consumo-de-drogas-entre-personas/
Ersöğütçü, F., & Karakaş, S. (2016). Social Functioning and Self-Esteem of Substance Abuse Patients. Archives of psychiatric nursing, 30(5), 587-592. https://doi.org/10.1016/j.apnu.2016.03.007
European Monitoring Centre for Drugs and Drug Addiction. (2021). Polydrug Use: Health and Social Responses. Publications Office. https://data.europa.eu/doi/10.2810/928644
Fatemeh, A., Fatemeh, R., Kazem, H., Mona, K., Reza, J., & Kheirollah, G. (2021). Drug-drug Interactions and Potentially Inappropriate Medications Among Elderly Outpatients. Brazilian Journal of Pharmaceutical Sciences, 57, 1-12.
https://doi.org/10.1590/s2175-97902020000418728
Gallardo-Peralta, L., Sánchez-Moreno, E., & Herrera, S. (2022). Aging and Family Relationships among Aymara, Mapuche and Non-Indigenous People: Exploring How Social Support, Family Functioning, and Self-Perceived Health Are Related to Quality of Life. International Journal of Environmental Research and Public Health, 19(15), 1-17. https://doi.org/10.3390/ijerph19159247
Gfroerer, J., Penne, M., Pemberton, M., & Folsom, R. (2003). Substance Abuse Treatment Need Among Older Adults in 2020: The Impact of The Aging Baby-Boom Cohort. Drug and Alcohol Dependence, 69(2), 127-135. https://doi.org/10.1016/s0376-8716(02)00307-1
Global Burden of Disease [GBD]. (2015). Global, Regional, and National Incidence, Prevalence, and Years Lived with Disability for 301 Acute and Chronic Diseases and Injuries in 188 Countries, 1990-2013: A Systematic Analysis for the Global Burden of Disease Study 2013. Lancet, 386(9995), 743-800. https://doi.org/10.1016/S0140-6736(15)60692-4
Gutiérrez-Valencia, M., Aldaz, P., Lacalle-Fabo, E., Contreras, B., Cedeño-Veloz, B. y Martínez-Velilla, N. (2019). Prevalencia de polifarmacia y factores asociados en adultos mayores en España: datos de la Encuesta Nacional de Salud 2017. Medicina Clínica, 153(4), 141-150. https://doi.org/10.1016/j.medcli.2018.12.013
Han, B., Moore, A., Sherman, S., & Palamar, J. (2018). Prevalence and Correlates of Binge Drinking Among Older Adults with Multimorbidity. Drug and Alcohol Dependence, 187, 48-54. https://doi.org/10.1016/j.drugalcdep.2018.01.038
Han, B., Moore, A., Sherman, S., Keyes, K., & Palamar, J. (2017). Demographic Trends of Binge Alcohol Use and Alcohol Use Disorders Among Older Adults in The United States, 2005-2014. Drug And Alcohol Dependence, 170, 198-207. https://doi.org/10.1016/j.drugalcdep.2016.11.003
Han, B., Gfroerer, J., & Colliver, J. (2010). Associations Between Duration of Illicit Drug Use and Health Conditions: Results from The 2005-2007 National Surveys on Drug Use and Health. Annals of Epidemiology, 20(4), 289-297.
https://doi.org/10.1016/j.annepidem.2010.01.003
Hayes, B., Klein-Schwartz, W., & Barrueto, F. (2007). Polypharmacy and the Geriatric Patient. Clinics in Geriatric Medicine, 23(2), 371-390. https://doi.org/10.1016/j.cger.2007.01.002
Hernández, F., Álvarez, MdelC., Martínez, G., Junco, V., Valdés, I. y Hidalgo, M. (2018). Polifarmacia en el anciano. Retos y soluciones. Revista Médica Electrónica, 40(6), 2053-2070. https://revmedicaelectronica.sld.cu/index.php/rme/article/view/2640
Heshmatifar N., Davarinia, A., Mohammadzadeh, Z., Moayed, L, Moradi, S, Rastagi, S et al. (2021). Prevalence and Factors Related to Self-Medication for COVID-19 Prevention in the Elderly. Salmand: Iranian Journal of Ageing, 16(1), 112-127. https://doi.org/10.32598/sija.16.1.2983.1
Homero, G. (2012). Polifarmacia y morbilidad en adultos mayores. Revista Médica Clínica Las Condes, 23(1), 31-35. https://www.elsevier.es/es-revista-revistamedica-clinica-las-condes-202-articulo-polifarmacia-morbilidad-adultosmayores-S0716864012702705
Jiang, Y., Jiang, T., Xu, L., & Ding, L. (2022). Relationship of Depression and Sleep Quality, Diseases and General Characteristics. World Journal of Psychiatry, 12(5), 722-738. https://doi.org/10.5498/wjp.v12.i5.722
Jyrkkä, J., Enlund, H., Korhonen, M., Sulkava, R., & Hartikainen, S. (2009). Polypharmacy Status as an Indicator of Mortality in an Elderly Population. Drugs & Aging, 26(12), 1039-1048. https://doi.org/10.2165/11319530-000000000-00000
Kaufmann, C., Malhotra, A., Yang, K., Han, B., Nafsu, R., Lifset, E., Nguyen, K., Sexton, M., & Moore, A. (2023). Cannabis Use for Sleep Disturbance Among Older Patients in a Geriatrics Clinic. International Journal of Aging & Human Development, 97(1), 3-17. https://doi.org/10.1177/00914150221128971
Keyes, K. (2023). Alcohol Use in the Older Adult US Population: Trends, Causes, and Consequences. Alcohol, 107, 28-31. https://doi.org/10.1016/j.alcohol.2022.05.005
Lindgren, K., Neighbors, C., Gasser, M., Ramirez, J., & Cvencek, D. (2017). A Review of Implicit and Explicit Substance Self-Concept as a Predictor of Alcohol and Tobacco Use and Misuse. The American Journal of Drug and Alcohol Abuse, 43(3), 237-246. https://doi.org/10.1080/00952990.2016.1229324
Marcos-Pardo, P., González-Gálvez, N., Carbonell-Baeza, A., Jiménez-Pavón, D., & Vaquero-Cristóbal, R. (2023). GDLAM and SPPB Batteries for Screening Sarcopenia in Community-Dwelling Spanish Older Adults: Healthy-Age Network Study. Experimental Gerontology, 172, 1-9. https://doi.org/10.1016/j.exger.2022.112044
Marengoni, A., Angleman, S., Melis, R., Mangialasche, F., Karp, A., Garmen, A., Meinow, B., & Fratiglioni, L. (2011). Aging with Multimorbidity: A Systematic Review of The Literature. Aging Research Reviews, 10(4), 430-439. https://doi.org/10.1016/j.arr.2011.03.003
Mattingly, D., Fleischer, N., Colston, D., & Mezuk, B. (2020). Perceived Racial Discrimination and Polysubstance Use Among African American and Afro-Caribbean Adults: Results from the National Survey of American
Life. Journal of Ethnicity in Substance Abuse, 21(4), 1-20. https://doi.org/10.1080/15332640.2020.1836700
Mendoza-Meléndez, M., Borges, G., Gallegos-Cari, A., García, J., Hernández- Llanes, N., Camacho-Solís, R. y Medina-Mora, M. (2015). Asociación del consumo de sustancias psicoactivas con el cuidado y la salud del adulto mayor. Salud mental, 38(1), 15-26. https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=56963
Ministerio de Justicia. (2023). Observatorio de Drogas de Colombia. Sustancias Psicoactivas. https://www.minjusticia.gov.co/programas-co/ODC/Paginas/Sustancias-Psicoactivas.aspx
Moral-García, J., González-Palomares, A., García-Cantó, E. y Tárrega-López, P. (2020). Riesgo de dependencia y autoestima en personas mayores de 60 años según la actividad física y el consumo farmacológico. Revista Española de Salud Pública, 94, 1-12. https://recyt.fecyt.es/index.php/RESP/article/view/83363
National Academies of Sciences, Engineering, and Medicine. (2020). Social Isolation and Loneliness in Older Adults: Opportunities for the Health Care System. The National Academies Press. https://doi.org/10.17226/25663
National Heart, Lung, and Blood Institute Temas de Salud. (2022). ¿Qué es la neumonía? https://www.nhlbi.nih.gov/health/pneumonia National Institute on Drug Abuse. [NIDA]. (2020). Substance Use in Older Adults Drug Facts. https://nida.nih.gov/publications/drugfacts/substance-use-in-older-adults-drugfacts.
National Institute on Drug Abuse [NIDA]. (2023). ¿Cómo se puede prevenir el uso indebido de medicamentos recetados? https://nida.nih.gov/publications/research-reports/misuse-prescription-drugs/how-can-prescription-drug-misuse-be-prevented
Organización Panamericana de la Salud [OPS]. (2023a). Uso de sustancias. https://www.paho.org/en/topics/substance-use.
Organización Panamericana de la Salud [OPS]. (2023b). Infecciones por coronavirus. https://www.paho.org/en/topics/coronavirus-infections.
Pereira, G., Silveira, K., Borges, C., & Oliveira, M. (2020). Clinical Characteristics of Drug Users Hospitalized in an Intensive Care Unit. Revista Eletrônica Saúde Mental Álcool e Drog, 16(2), 34-41. https://www.revistas.usp.br/smad/
article/download/158506/163164/431998
Pinelo, K., Pavón-León, P., Salas-García, B., De San Jorge-Cárdenas, X., Beverido, P. y Mejorada-Fernández, J. (2022). Consumo de drogas legales e ilegales y síntomas de depresión en adultos mayores usuarios de Facebook durante
la pandemia por SARS-CoV-2 en México. Revista Española de Geriatría y Gerontología, 57(5), 273-277. https://doi.org/10.1016/j.regg.2022.07.002
Qato, D., Alexander, G., Conti, R., Johnson, M., Schumm, P., & Lindau, S. (2008). Use of Prescription and Over-The-Counter Medications and Dietary Supplements Among Older Adults in the United States. JAMA, 300(24),
2867-2878. https://doi.org/10.1001/jama.2008.892
Ramadan, M., Banta, J., Bahjri, K., & Montgomery, S. (2021). Marijuana Users are Likely to Report Opioid Misuse Among Adults Over 50 Years in Representative Sample of the United States (2002-2014). Journal of Addictive Diseases, 39(1), 66-73. https://doi.org/10.1080/10550887.2020.1816117
Riquelme, N., Fraile, C. y Pimenta, A. (2005). Influencia del consumo de sustancias psicoactivas en el ámbito familiar sobre la autoestima de los escolares. Revista Latino-am Enfermagem, 13(1), 798-805. https://www.redalyc.org/articulo.oa?id=281421851006
Ruiz-Jasso, L., Sifuentes-Leura, D., Acevedo-Alemán, J., Torres-Obregón, R. y del Bosque-Moreno, J. (2022). Fragilidad, polifarmacia y riesgo de caídas en personas adultas mayores. Gerokomos, 33(2), 95-98. https://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S1134-928X2022000200006
Sánchez-Rodríguez, J., Escare-Oviedo, C., Castro-Olivares, V., Robles-Molina,C., Vergara-Martínez, M. y Jara-Castillo, C. (2019). Polifarmacia en adulto mayor, impacto en su calidad de vida. Revisión de la literatura. Revista Salud Pública, 21(2), 271-277. https://doi.org/10.15446/rsap.V21n2.76678
Schepis, T., Simoni-Wastila, L., & McCabe, S. (2019). Prescription Opioid and Benzodiazepine Misuse is Associated with Suicidal Ideation in Older Adults. International Journal of Geriatric Psychiatry, 34(1), 122-129. https://doi.org/10.1002/gps.4999
Sella, E., Cellini, N., & Borella, E. (2022). How Elderly People's Quality of Life Relates to Their Sleep Quality and Sleep-Related Beliefs. Behavioral Sleep Medicine, 20(1), 112-124. https://doi.org/10.1080/15402002.2021.1895792
Shorr, R., Hoth, A., & Rawls, N. (2007). Drugs for the Geriatric Patient. Saunders Elsevier.
Silva, D., Souza-Talarico, J., Santos, J., & Duarte, Y. (2023). Family Dysfunction and Cognitive Decline in Aging: the "Health, Wellbeing, and Aging" (SABE) Longitudinal Population-Based Study. Dementia & Neuropsychologia, 17, 1-9.
https://doi.org/10.1590/1980-5764-DN-2022-0109
Sim, M., Hulse, G., & Khong, E. (2004). Alcohol and Other Drug Use in Later Life. Australian Family Physician, 33(10), 820-824. https://www.racgp.org.au/afp/backissues/2004/14374
Spadola, C., Wagner, E., Slavish, D., Washburn, M., Ogeil, R., Burke, S., Grudzien, A., & Zhou, E. (2023). Sleep and Substance Use: Practice Considerations for Social Workers. Journal of Social Work Practice in the Addictions, 23(1),
24-38. https://doi.org/10.1080/1533256X.2022.2159642
Substance Abuse and Mental Health Services Administration [SAMHSA]. (2024). Behavioral health among older adults: Results from the 2021 and 2022 National Surveys on Drug Use and Health. Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. https://www.samhsa.gov/data/report/older-adult-behavioral-health-report-2021-2022
Substance Abuse and Mental Health Services Administration, & Center for Behavioral Health Statistics and Quality. (2020). Results from the 2018 National Survey on Drug Use and Health: Detailed Tables. Prevalence Estimates, Standard Errors, p Values, and Sample Sizes. https://www.samhsa.gov/data/
Wolde, A. (2023). Alcohol Use Disorder and Associated Factors Among Elderly in Ethiopia. Substance Abuse: Research and Treatment, 17, 1-8. https://doi.org/10.1177/11782218231158031
Xia, M., & Yang, C. (2019). The Relationship Among Social Support, Self-Esteem, Affect Balance and Loneliness in Individuals with Substance Use Disorders in China. Journal of Community Psychology, 47(5), 1269-1281. https://doi.org/10.1002/jcop.22190
Published
Issue
Section
License
Copyright (c) 2025 Alejandra Segura-Cardona, Doris Cardona, Diana Muñoz-Rodríguez, Carlos Robledo-Marín, Emilio Salazar-Flórez, Angela Segura-Cardona

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Once the manuscript is approved, the authors should file and sign the Right Transfer Format.